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CAY10616 Exclusive

Cayman Chemical Item Number 13291

(CAS 586410-08-4)

CAY10616 (CAS 586410-08-4)

See more	Antioxidants (62) Inhibitors (493) Apoptosis (183) Cancer (606)

Description

Resveratrol is a natural polyphenolic antioxidant that has anti-cancer properties. CAY10616 is an analog of resveratrol which is a potent inducer of apoptosis in promyelocytic leukemia HL-60 cells (IC₅₀ = 40 nM versus 50 μM for resveratrol).¹ In addition, CAY10616 induces apoptosis (IC₅₀ = 30 nM) in HL60R, a cell line derived from HL-60 that expresses a multidrug-resistance phenotype (resistant to daunorubicin, etoposide, and citarabine).¹

1 Roberti, M., Pizzirani, D., Simoni, D., et al. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. J Med Chem 46 3546-3554 (2003).

Formal Name	5-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxy-phenol
CAS Number	586410-08-4
Molecular Formula	C₁₇H₁₈O₄
Formula Weight	286.3
Formulation	A solution in methyl acetate
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard COc1cc(\C=C\c2ccc(OC)c(O)c2)cc(OC)c1

Background Reading

Roberti, M., Pizzirani, D., Simoni, D., et al. Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents. J Med Chem 46 3546-3554 (2003).

CAY10616 is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 mg	$21.00		$0.00
5 mg	$95.00		$0.00
10 mg	$168.00		$0.00
25 mg	$368.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

cis-Resveratrol

cis-trismethoxy Resveratrol

trans-Resveratrol

trans-Resveratrol-d₄

trans-trismethoxy Resveratrol-d₄

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Batch-specific Information

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