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Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
Pifithrin-
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Description
1 Komarov, P.G., Komarova, E.A., Kondratov, R.V., et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285 1733-1737 (1999).
2
Lorenzo, E., Ruiz-Ruiz, C., Quesada, A.J., et al. Doxorubicin induces apoptosis and CD95 gene expressionin human primary endothelial cells through a p53-
3
Sohn, D., Graupner, V., Neise, D., et al. Pifithrin-
| Formal Name | 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-ethanone, monohydrobromide |
|---|---|
| CAS Number | 63208-82-2 |
| Molecular Formula | C16H18N2OS · HBr |
| Formula Weight | 367.3 |
| Formulation | A crystalline solid |
| Purity | ≥95% |
| Stability | 2 years |
| Storage | -20°C |
| Shipping | Room temperature in continental US; may vary elsewhere |
| SMILES |
Copy SMILES to clipboard
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Background Reading
Sohn, D., Graupner, V., Neise, D., et al. Pifithrin-
Komarov, P.G., Komarova, E.A., Kondratov, R.V., et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285 1733-1737 (1999).
Lorenzo, E., Ruiz-Ruiz, C., Quesada, A.J., et al. Doxorubicin induces apoptosis and CD95 gene expressionin human primary endothelial cells through a p53-
Pifithrin-α is available in the following screening library:
| Size | Price | Quantity | Subtotal |
|---|---|---|---|
| 5 mg | $51.00 | $0.00 | |
| 10 mg | $97.00 | $0.00 | |
| 25 mg | $230.00 | $0.00 | |
| 50 mg | $408.00 | $0.00 | |
| Bulk | Contact | ||
| Cart Total | $0.00 |
This product is available in custom sizes and/or larger quantities.
Please contact our Sales Department for a quote or to purchase.
Pricing updated 2012-05-26. Prices are subject to change without notice.
To ask for assistance with one of our products please contact a Technical Support Scientist.
Warning This product is not for human or veterinary use.
Related Products
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(±)- |
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p53 Cell- |
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p53 Total and p53 (Phospho- |
| p53 Transcription Factor Assay Kit |
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Pifithrin- |
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PRIMA- |
| RITA |
Downloads
 | Download Product Insert 126 Kb PDF |
| Download Material Safety Data Sheet (MSDS) 16 Kb PDF |
|
Printer-friendly version of this page small PDF (usually less than 100 Kb) |
| • US Letter paper 8½″ × 11″ | |
| • A4 paper 21cm × 29.7cm | |
| Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details. |
Batch-specific Information
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.
Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
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