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Lignoceric Acid

Cayman Chemical Item Number 13353

FL 88 (CAS 557-59-5)

Lignoceric Acid (CAS 557-59-5)

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Synonyms
  • FL 88
Formal Name tetracosanoic acid
CAS Number 557-59-5
Molecular Formula C24H48O2
Formula Weight 368.6
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Wet Ice in continental US; may vary elsewhere
SMILES CCCCCCCCCCCCCCCCCCCCCCCC(=O)​O

Description

Lignoceric acid is a 23-carbon saturated (23:0) fatty acid. In mammals, it is synthesized during brain development and is found in cerebrosides.1 The deficient peroxisomal oxidation of very-long-chain fatty acids, including lignoceric acid, contributes to certain syndromes, including Zellweger cerebro-hepato-renal syndrome and X chromosome-linked adrenoleukodystrophy.2 Lignoceric acid is also a by-product of lignin production.

1 Bourre, J., Paturneau-Jouas, M.Y., Daudu, O.L., et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesisand microsomal malonyl-CoA chain-elongating systemin relation to myelination. Eur J Biochem 72 41-47 (1977).

2 Singh, I., Moser, A.E., Goldfischer, S., et al. Lignoceric acid is oxidized in the peroxisome: Implications for the Zellweger cerebro-hepato-renal syndrome andadrenoleukodystrophy. Proc Natl Acad Sci USA 81 4203-4207 (1984).

Related Articles

Bourre, J., Paturneau-Jouas, M.Y., Daudu, O.L., et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesisand microsomal malonyl-CoA chain-elongating systemin relation to myelination. Eur J Biochem 72 41-47 (1977).

Singh, I., Moser, A.E., Goldfischer, S., et al. Lignoceric acid is oxidized in the peroxisome: Implications for the Zellweger cerebro-hepato-renal syndrome andadrenoleukodystrophy. Proc Natl Acad Sci USA 81 4203-4207 (1984).

Pricing updated 2010-09-06. Prices are subject to change without notice.

Pricing is for North America only. Other customers should contact a distributor in their region.

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Related Products

Hexacosanoic Acid
Myristic Acid

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