Lignoceric Acid
Cayman Chemical Item Number 13353
FL 88
(CAS 557-59-5)
Lignoceric Acid
(CAS 557-59-5)
| Synonyms |
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| Formal Name |
tetracosanoic acid |
| CAS Number |
557-59-5 |
| Molecular Formula |
C24H48O2 |
| Formula Weight |
368.6 |
| Formulation |
A crystalline solid |
| Purity |
≥98% |
| Stability |
2 years |
| Storage |
-20°C |
| Shipping |
Wet Ice
in continental US; may vary elsewhere
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| SMILES |
CCCCCCCCCCCCCCCCCCCCCCCC(=O)O
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Description
Lignoceric acid is a 23-carbon saturated (23:0) fatty acid. In mammals, it is synthesized during brain development and is found in cerebrosides.1 The deficient peroxisomal oxidation of very-long-chain fatty acids, including lignoceric acid, contributes to certain syndromes, including Zellweger cerebro-hepato-renal syndrome and X chromosome-linked adrenoleukodystrophy.2 Lignoceric acid is also a by-product of lignin production.
1
Bourre, J., Paturneau-Jouas, M.Y., Daudu, O.L., et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesisand microsomal malonyl-CoA chain-elongating systemin relation to myelination. Eur J Biochem 72 41-47 (1977).
2
Singh, I., Moser, A.E., Goldfischer, S., et al. Lignoceric acid is oxidized in the peroxisome: Implications for the Zellweger cerebro-hepato-renal syndrome andadrenoleukodystrophy. Proc Natl Acad Sci USA 81 4203-4207 (1984).
Related Articles
Bourre, J., Paturneau-Jouas, M.Y., Daudu, O.L., et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesisand microsomal malonyl-CoA chain-elongating systemin relation to myelination. Eur J Biochem 72 41-47 (1977).
Singh, I., Moser, A.E., Goldfischer, S., et al. Lignoceric acid is oxidized in the peroxisome: Implications for the Zellweger cerebro-hepato-renal syndrome andadrenoleukodystrophy. Proc Natl Acad Sci USA 81 4203-4207 (1984).
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