Lignoceric acid is a 24-carbon saturated (24:0) fatty acid. In mammals, it is synthesized during brain development and is found in cerebrosides.1 The deficient peroxisomal oxidation of very-long-chain fatty acids, including lignoceric acid, contributes to certain syndromes, including Zellweger cerebro-hepato-renal syndrome and X chromosome-linked adrenoleukodystrophy.2 Lignoceric acid is also a by-product of lignin production.
1
Bourre, J., Paturneau-Jouas, M.Y., Daudu, O.L., et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesisand microsomal malonyl-CoA chain-elongating systemin relation to myelination. Eur J Biochem7241-47(1977).
2
Singh, I., Moser, A.E., Goldfischer, S., et al. Lignoceric acid is oxidized in the peroxisome: Implications for the Zellweger cerebro-hepato-renal syndrome andadrenoleukodystrophy. Proc Natl Acad Sci USA814203-4207(1984).
Synonyms
FL 88
Formal Name
tetracosanoic acid
CAS Number
557-59-5
Molecular Formula
C24H48O2
Formula Weight
368.6
Formulation
A crystalline solid
Purity
≥98%
Stability
2 years
Storage
-20°C
Shipping
Wet ice
in continental US; may vary elsewhere
SMILES
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CCCCCCCCCCCCCCCCCCCCCCCC(=O)O
Background Reading
Bourre, J., Paturneau-Jouas, M.Y., Daudu, O.L., et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesisand microsomal malonyl-CoA chain-elongating systemin relation to myelination. Eur J Biochem7241-47(1977).
Singh, I., Moser, A.E., Goldfischer, S., et al. Lignoceric acid is oxidized in the peroxisome: Implications for the Zellweger cerebro-hepato-renal syndrome andadrenoleukodystrophy. Proc Natl Acad Sci USA814203-4207(1984).
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50 mg
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100 mg
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250 mg
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500 mg
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