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13360 8-iso Prostaglandin E1
Ovinonic acid; 8-iso PGE1; 8-epi PGE1
(CAS 21003-46-3)
8-iso Prostaglandin E1 Workbook Links
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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin.1 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 µg/ml.2 It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.3
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1
Morrow, J.D., Hill, K.E., Burk, R.F., et al. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA 87 9383-9387 (1990).
2
Taylor, P.L. The 8-isoprostaglandins: Evidence for eight compounds in human semen. Prostaglandins 17 259-267 (1979).
3
Nakano, J., Kessinger, J.M. Effects of 8-isoprostaglandin E1 on the systemic and pulmonary circulations in dogs. Proc Soc Exp Biol Med 133 1314-1317 (1970).
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Purchase 13360 8-iso Prostaglandin E1
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-19.
Prices are subject to change without notice.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.
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