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Atrazine

Cayman Chemical Item Number 13375

(CAS 1912-24-9)

Atrazine (CAS 1912-24-9)

See more	Inhibitors (493) Plant Growth Regulators (14) Cancer (606) Endocrinology (335) Plant Biology (27)

Description

Atrazine is an herbicide that is effective in controlling a broad range of weeds. Atrazine has been reported to cause cancer in certain laboratory animals, have diverse effects on the reproductive system in animals and humans, and disrupt the normal function of the endocrine system.^1,2,3 Chronic exposure of frogs to atrazine significantly alters the expression of several genes, especially those involved in growth and metabolism.⁴ The United States Environmental Protection Agency currently allows the use of atrazine as an herbicide but in 2009, launched a comprehensive new evaluation to determine its effects on humans.

1 Eldridge, J.C., Wetzel, L.T., Stevens, J.T., et al. The mammary tumor response in triazine-treated female rats: A threshold-mediated interaction with strain and species-specific reproductive senescence. Steroids 64 672-678 (1999).

2 Goldman, J.M., Stoker, T.E., and Cooper, R.L. Neuroendocrine and reproductive effects of contemporary-use pesticides. Toxicol Ind Health 15 26-36 (1999).

3 Hayes, T.B., Collins, A., Lee, M., et al. Hermaphroditic, demasculinized frogs after exposure to the herbicide atrazine at low ecologically relevant doses. Proc Natl Acad Sci USA 99(8) 5476-5480 (2002).

4 Langerveld, A.J., Celestine, R., Zaya, R., et al. Chronic exposure to high levels of atrazine alters expression of genes that regulate immune and growth-related functions in developing Xenopus laevis tadpoles. Environ Res 109 379-389 (2009).

Formal Name	6-chloro-N2-ethyl-N4-(1-methylethyl)-1,3,5-triazine-2,4-diamine
CAS Number	1912-24-9
Molecular Formula	C₈H₁₄ClN₅
Formula Weight	215.7
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCNc1nc(NC(C)C)nc(Cl)n1

Background Reading

Eldridge, J.C., Wetzel, L.T., Stevens, J.T., et al. The mammary tumor response in triazine-treated female rats: A threshold-mediated interaction with strain and species-specific reproductive senescence. Steroids 64 672-678 (1999).

Goldman, J.M., Stoker, T.E., and Cooper, R.L. Neuroendocrine and reproductive effects of contemporary-use pesticides. Toxicol Ind Health 15 26-36 (1999).

Langerveld, A.J., Celestine, R., Zaya, R., et al. Chronic exposure to high levels of atrazine alters expression of genes that regulate immune and growth-related functions in developing Xenopus laevis tadpoles. Environ Res 109 379-389 (2009).

Size	Price	Quantity	Subtotal
100 mg	$14.00		$0.00
250 mg	$33.00		$0.00
500 mg	$63.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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