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Join us! · SLAS2012 1st Annual Conference & Exhibition · San Diego, California · February 4-8, 2012 · Booth 445

S1P2 Polyclonal Antibody

Cayman Chemical Item Number 13488

Sphingosine-1-phosphate Receptor 2; S1PR2; EDG-5

S1P2 Polyclonal Antibody

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Description

Antigen: synthetic peptide from human S1P2 amino acids 325-343 · Host: rabbit · Application(s): WB · S1P2 is a membrane protein belonging to the EDG family of extracellular G protein-coupled receptors. It acts as a receptor for the bioactive lipid sphingosine 1-phosphate (S1P) and participates in S1P-induced cell proliferation, survival, and transcriptional activation. It shares 92% amino acid identity with rat H218 and approximately 44% identity with the human S1P receptors EDG-1 and EDG-3. Though the role of S1P2 in vascular permeability is not clear, reports suggest that it regulates PTEN by a Rho GTPase-dependent pathway to inhibit cell migration. S1P2 also plays an important role in normal vascularization and hypoxia-triggered pathological angiogenesis of the mouse retina. The gene for human S1P2 protein is localized on chromosomal region 19p13.2. The protein is usually expressed in human brain and heart.
Synonyms
  • Sphingosine-1-phosphate Receptor 2
  • S1PR2
  • EDG-5
Formulation 100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human S1P2 +
Monkey S1P2 +
Mouse S1P2 +
Rat S1P2 +
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Size Price Quantity Subtotal
1 ea $245.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-04. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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S1P3 Polyclonal Antibody
S1P4 Polyclonal Antibody
S1P5 Polyclonal Antibody
Sphingosine-1-Phosphate
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