13488  S1P2 Polyclonal Antibody

Sphingosine-1-phosphate Receptor 2; S1PR2; EDG-5

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• See more Western Blot; Antibodies; Ceramides/Sphingolipids; Cell Biology; Immunology

Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Antigen: synthetic peptide from human S1P2 amino acids 325-343 · Host: rabbit · Application(s): WB · S1P2 is a membrane protein belonging to the EDG family of extracellular G protein-coupled receptors. It acts as a receptor for the bioactive lipid sphingosine 1-phosphate (S1P) and participates in S1P-induced cell proliferation, survival, and transcriptional activation. It shares 92% amino acid identity with rat H218 and approximately 44% identity with the human S1P receptors EDG-1 and EDG-3. Though the role of S1P2 in vascular permeability is not clear, reports suggest that it regulates PTEN by a Rho GTPase-dependent pathway to inhibit cell migration. S1P2 also plays an important role in normal vascularization and hypoxia-triggered pathological angiogenesis of the murine retina. The gene for human S1P2 protein is localized on chromosomal region 19p13.2. The protein is usually expressed in human brain and heart.


Purchase 13488 S1P2 Polyclonal Antibody

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Pricing updated 2010-03-19.
Prices are subject to change without notice.

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