S1P₅ Polyclonal Antibody

Cayman Chemical Item Number 13490

EDG-8; S1PR5; Sphingosine-1-phosphate Receptor 5

S1P5 Polyclonal Antibody

See more	Immunohistochemistry (208) Western Blot (557) Antibodies (630) Ceramides/Sphingolipids (55) Cell Biology (282) Immunology (181)

Description

Antigen: synthetic peptide from human S1P₅ within the region amino acids 1-50 · Host: rabbit · Application(s): WB and IHC · Sphingosine 1-phosphate (S1P) receptor EDG-8 is a multi-pass membrane protein belonging to the G protein-coupled receptor 1 family and coupled to both the Gi/0a and G12 subclass of heteromeric G-proteins. EDG-8 acts as a receptor for the bioactive sphingolipid S1P as well as for lysophosphatidic acid (LPA) and gives diverse physiological effects on most types of cells and tissues. EDG-8 may also play a regulatory role in the transformation of radial glial cells into astrocytes and affect proliferative activity of these cells. It is widely expressed in white matter tracts of brain, spleen, peripheral blood leukocytes, placenta, lung, aorta, and fetal spleen. Over expression of EDG-8 leads to a lymphoproliferative disorder often associated with the autoimmune disease known as leukemic large granular lymphocyte (LGL).

Synonyms

EDG-8
S1PR5
Sphingosine-1-phosphate Receptor 5

Formulation

100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide

Stability

1 year

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Specificity

Human S1P5	+
Canine S1P5	+
Monkey S1P5	+
Mouse S1P5	+
Rat S1P5	+

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Size	Price	Quantity	Subtotal
1 ea	$245.00		$0.00
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		Cart Total	$0.00

Pricing updated 2012-02-08. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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S1P5 Polyclonal Antibody

S1P5 Polyclonal Antibody

Description

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S1P₅ Polyclonal Antibody