Cayman Chemical | S1P5 Polyclonal Antibody | Description • Sphingosine-1-phosphate Receptor 5; EDG-8; S1PR5

13490 S1P₅ Polyclonal Antibody

Sphingosine-1-phosphate Receptor 5; EDG-8; S1PR5

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• See more Immunohistochemistry; Western Blot; Antibodies; Ceramides/Sphingolipids; Cell Biology; Immunology

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Antigen: synthetic peptide from human S1P₅ within the region amino acids 1-50 · Host: rabbit · Application(s): WB and IHC · Sphingosine 1-phosphate (S1P) receptor EDG-8 is a multi-pass membrane protein belonging to the G protein-coupled receptor 1 family and coupled to both the Gi/0a and G12 subclass of heteromeric G-proteins. EDG-8 acts as a receptor for the bioactive sphingolipid S1P as well as for lysophosphatidic acid (LPA) and gives diverse physiological effects on most types of cells and tissues. EDG-8 may also play a regulatory role in the transformation of radial glial cells into astrocytes and affect proliferative activity of these cells. It is widely expressed in white matter tracts of brain, spleen, peripheral blood leukocytes, placenta, lung, aorta, and fetal spleen. Over expression of EDG-8 leads to a lymphoproliferative disorder often associated with the autoimmune diease known as leukemic large granular lymphocyte (LGL).

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Purchase 13490 S1P₅ Polyclonal Antibody

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

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Warning This product is not for human or veterinary use.

Pricing updated 2010-03-16.
Prices are subject to change without notice.

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