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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

PRMT4 Polyclonal Antibody

Cayman Chemical Item Number 13552

CARM1; Protein Arginine Methyltransferase 4

PRMT4 Polyclonal Antibody

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Description

Antigen: human PRMT4 amino acid sequences 45-69 and 595-608 · Host: rabbit · Application(s): WB · Protein arginine methylation is an important post-translational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT4, also known as coactivator-associated arginine methyltransferase-1 (CARM1), belongs to a family of proteins that catalyzes the methylation of arginine residues. The PRMT proteins are recuited by C-terminal activation domain-2 of the steroid receptor coactivator (SRC) GRIP-1, whereas p300 interacts with activation domain-1 in the C-terminus. CARM1 can methylate histone H3 in vitro, and a mutation in the putative S-adenosylmethionine binding domain of CARM1 substantially reduces both methyltransferase and coactivator activities suggesting the coactivator-mediated methylation of proteins in the transcription machinery may contribute to transcriptional regulation.
Synonyms
  • CARM1
  • Protein Arginine Methyltransferase 4
Formulation 100 µg of protein G-purified IgG in 200 µl of PBS containing 0.05% BSA and 0.05% mg/ml sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Human PRMT4 +
Size Price Quantity Subtotal
1 ea $224.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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