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13553 LSD1 Polyclonal Antibody (aa 400-450)
LSD1 Polyclonal Antibody (aa 400-450) Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
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Antigen:
synthetic peptide from a portion of human LSD1 amino acids 400-450
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Host:
rabbit
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Application(s):
WB
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LSD1 the first known lysine-specific histone demethylase, is an
866 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain, a FAD-binding motif and an amine oxidase domain. This protein is ubiquitously expressed and is a component of several histone deacetylase complexes. LSD1 acts as a component of the CoREST and other transcriptional co-repressor complexes and also plays an important role in silencing neuronal-specific genes in non-neuronal cells. It is also known to demethylate Lys4 of histone H3, a specific tag for epigenetic transcriptional activation. Reports suggest that that LSD1 plays an important role in stimulating androgen-receptor-dependent transcription coverting oxygen to hydrogen peroxide (might use alternative electron acceptors). Along with nuclear FHL2, LSD1 serves as a novel biomarker predictive for prostate cancer.
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Purchase 13553 LSD1 Polyclonal Antibody (aa 400-450)
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
Please contact our
Sales Department
for a quote or to purchase.
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Warning This product is not for human or veterinary use.
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Pricing updated 2010-03-19.
Prices are subject to change without notice.
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