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(+)-CP 55,940 Exclusive

Cayman Chemical Item Number 13608

(+)-CP 55,940

See more	Cannabinoids (296) Forensic Science (306) Pain (144)

Description

(±)-CP 55,940 is a bicyclic mimetic of Δ⁹-THC that binds both cannabinoid receptors and has potent analgesic properties.^1,2,3 The isomer (−)-CP 55,940, which structurally resembles the A and C ring of Δ⁹-THC, is a potent analgesic.² (+)-CP 55,940 is an enantiomer purified from the (±)-CP 55,940 racemic mixture. The functional characteristics of this isomer have not been studied. However, there is no significant difference between the racemate and (−) isomer in analgesic activity in four of five tests, suggesting that (+)-CP 55,940 is biologically active.²

1 Devane, W.A., Dysarz, F.A., Johnson, M.R., et al. Determination and characterization of a cannabinoid receptor in rat brain. Mol Pharmacol 34 605-613 (1988).

2 Howlett, A.C., Johnson, M.R., Melvin, L.S., et al. Nonclassical cannabinoid analgetics inhibit adenylate cyclase: Development of a cannabinoid receptor model. Mol Pharmacol 33 297-302 (1987).

3 Pertwee, R.G. Pharmacology of cannabinoid receptor ligands. Curr Med Chem 6 635-664 (1999).

Formal Name	2-((1S,2S,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol
Molecular Formula	C₂₄H₄₀O₃
Formula Weight	376.6
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O[C@@H]1C[C@H](C2=CC=C(C(C)(C)CCCCCC)C=C2O)[C@@H](CCCO)CC1

Background Reading

Devane, W.A., Dysarz, F.A., Johnson, M.R., et al. Determination and characterization of a cannabinoid receptor in rat brain. Mol Pharmacol 34 605-613 (1988).

Howlett, A.C., Johnson, M.R., Melvin, L.S., et al. Nonclassical cannabinoid analgetics inhibit adenylate cyclase: Development of a cannabinoid receptor model. Mol Pharmacol 33 297-302 (1987).

Pertwee, R.G. Pharmacology of cannabinoid receptor ligands. Curr Med Chem 6 635-664 (1999).

(+)-CP 55,940 is available in the following screening library:

Cannabinoid Agonist Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 mg	$26.00		$0.00
5 mg	$117.00		$0.00
10 mg	$208.00		$0.00
25 mg	$455.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Featured Products	Mojo
(−)-CP 55,940 An agonist of CB1 and CB2	30.013067923302
(±)-CP 55,940 Exclusive A potent, non-selective CB receptor agonist	24.597446286065
(±)5-epi CP 55,940 By-product of synthesis to be used as analytical standard	7.455193370166

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