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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

JWH 250

Cayman Chemical Item Number 13634

(CAS 864445-43-2)

JWH 250 (CAS 864445-43-2)

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Description

JWH 250 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB1) and the peripheral cannabinoid (CB2) receptors. The affinities of JWH 250 for both CB1 (Ki = 11 nM) and CB2 (Ki = 33 nM) are comparable to those of the traditional cannabinoid, Δ9-tetrahydrocannabinol (Δ9-THC; Ki = 40.7 and 36.4 nM, respectively).1

1 Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett 15 4110-4113 (2005).

Formal Name 1-​(1-​pentyl-​1H-​indol-​3-​yl)-​2-​(2-​methoxyphenyl)-​ethanone
CAS Number 864445-43-2
Molecular Formula C22H25NO2
Formula Weight 335.2
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCN1C2=CC=CC=C2C(C(CC3=C(OC)​C=CC=C3)​=O)​=C1

Background Reading

De Freitas, G.B.L., da Silva, L.L., Romeiro, N.C., et al. Development of CoMFA and CoMSIA models of affinity and selectivity for indole ligands of cannabinoid CB1 and CB2 receptors. Eur J Med Chem 44 2482-2496 (2009).

Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett 15 4110-4113 (2005).

JWH 250 is available in the following screening library:

Size Price Quantity Subtotal
5 mg $56.00 $0.00
10 mg $106.00 $0.00
25 mg $252.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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