Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

15-keto Prostaglandin E₁

Cayman Chemical Item Number 13680

15-keto PGE₁ (CAS 22973-19-9)

15-keto Prostaglandin E1 (CAS 22973-19-9)

See more	Prostaglandins (513)

Description

15-keto PGE₁ is the inactive metabolite of PGE₁ produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE₁.^1,2

1 Westwick, J. The effect of pulmonary metabolites of prostaglandins E₁, E₂ and F_2α on ADP-induced aggregation of human and rabbit platelets. Br J Pharmacol 58 297P-298P (1976).

2 Änggård, E. The biological activities of three metabolites of prostaglandin E₁. Acta Physiol Scand 66 509-510 (1966).

Synonyms	15-keto PGE1
Formal Name	9,15-dioxo-11α-hydroxy-prost-13E-en-1-oic acid
CAS Number	22973-19-9
Molecular Formula	C₂₀H₃₂O₅
Formula Weight	352.5
Formulation	A solution in methyl acetate
Purity	>98%
λ_max	229 nm
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCC(=O)\C=C/[C@H]1C(O)CC(=O)C1CCCCCCC(=O)O

Background Reading

Hamberg, M., and Samuelsson, B. On the metabolism of prostaglandin E₁ and E₂ in the guinea pig. J Biol Chem 247 3495-3502 (1972).

Änggård, E. The biological activities of three metabolites of prostaglandin E₁. Acta Physiol Scand 66 509-510 (1966).

Westwick, J. The effect of pulmonary metabolites of prostaglandins E₁, E₂ and F_2α on ADP-induced aggregation of human and rabbit platelets. Br J Pharmacol 58 297P-298P (1976).

Hamberg, M., and Samuelsson, B. On the metabolism of prostaglandins E₁ and E₂ in man. J Biol Chem 246 6713-6721 (1971).

Show all 4 Hide all but first 3

15-keto Prostaglandin E1 is available in the following screening libraries:

Size	Price	Quantity	Subtotal
500 µg	$47.00		$0.00
1 mg	$89.00		$0.00
5 mg	$376.00		$0.00
10 mg	$658.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

Prostaglandin E₁

Downloads

	Download Product Insert 178 Kb PDF
	Download Material Safety Data Sheet (MSDS) 17 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs	Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases	Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule	Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

15-keto Prostaglandin E1