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15(S)-15-methyl Prostaglandin E1

Cayman Chemical Item Number 13730

15(S)-15-methyl PGE1 (CAS 35700-26-6)

15(S)-15-methyl Prostaglandin E1 (CAS 35700-26-6)

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Description

15(S)-15-methyl PGE1 is a metabolically stable synthetic analog of PGE1. In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.1

1 Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).

Synonyms
  • 15(S)-15-methyl PGE1
Formal Name 9-​oxo-​11α,​15S-​dihydroxy-​15-​methyl-​prost-​13E-​en-​1-​oic acid
CAS Number 35700-26-6
Molecular Formula C21H36O5
Formula Weight 368.5
Formulation A solution in methyl acetate
Purity >98%
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCC[C@]​(C)​(O)​\C=C\[C@H]​1C(O)​CC(=O)​C1CCCCCCC(=O)​O

Background Reading

Yankee, E.W., Axen, U., and Bundy, G.L. Total synthesis of 15-methylprostaglandins. J Am Chem Soc 96 5865-5876 (1974).

Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).

15(S)-15-methyl Prostaglandin E1 is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $76.00 $0.00
5 mg $342.00 $0.00
10 mg $608.00 $0.00
50 mg $2,660.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Prostaglandin E1

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