Akt3 Polyclonal Antibody
Cayman Chemical Item Number 13737
Akt3 Polyclonal Antibody
Description
Antigen:
synthetic peptide from human Akt3 amino acids 119-136; this sequence is identical in human, mouse, and rat
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Host:
rabbit
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Application(s):
WB
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Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3-kinase and Akt/PKB kinase activity. There are three known isoforms of this enzyme in mammalian cells (1/a, 2/b, and 3/g). Akt1, 2, and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for its activity.
| Formulation |
100 µg of protein G-purified IgG in 200 µl PBS containing 0.02% sodium azide and 0.01% BSA |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
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| Specificity |
| Human Akt3 |
+ |
| Mouse Akt3 |
+ |
| Rat Akt3 |
+ |
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Pricing updated 2012-02-12.
Prices are subject to change without notice.
To ask for assistance with one of our products please contact a Technical Support Scientist.
Warning This product is not for human or veterinary use.
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.
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