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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

FoxP3/Scurfin Polyclonal Antibody

Cayman Chemical Item Number 13739

FoxP3/Scurfin Polyclonal Antibody

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Description

Antigen: synthetic peptide corresponding to the exon 2 deletion site was used as immunogen · Host: rabbit · Application(s): IHC and WB · One of the many immunotolerance mechanisms that the immune system has developed to distinguish between self and non-self antigens are regulatory T-cells or Tregs. Several elegant experiments using transgenic mice and retrovirus-mediated over-expression studies have led to the identification of FoxP3, a transcription factor, as a specific molecular marker essential for the development and function of Tregs. The primary evidence regarding the involvement of FoxP3 in the development of Tregs was provided in patients suffering from IPEX, a rare and fatal human autoimmune disease. The emergence of Tregs and the role of FoxP3 as a critical player in the negative control of various normal and pathological immune responses holds great promise for the development of novel therapies for autoimmune diseases.
Formulation 100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Bovine FoxP3/Scurfin +
Chicken FoxP3/Scurfin +
Equine FoxP3/Scurfin +
Human FoxP3/Scurfin +
Porcine FoxP3/Scurfin +
Rat FoxP3/Scurfin +
Rhesus monkey FoxP3/Scurfin +
Show all 7 Hide all but first 3
Size Price Quantity Subtotal
1 ea $224.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

FoxP3Δ2 (exon 2 deleted) Specific Monoclonal Antibody (Clone 16J4G6)
FoxP3Δ2 (exon 2 deleted) Specific Monoclonal Antibody (Clone 16J4G6) (azide free)

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