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16,16-dimethyl Prostaglandin E1

Cayman Chemical Item Number 13750

16,16-dimethyl PGE1 (CAS 41692-15-3)

16,16-dimethyl Prostaglandin E1 (CAS 41692-15-3)

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Description

16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1. It induces human vascular smooth muscle contractions in vitro. It is 2, 3, and 6 times more potent than PGF in contracting tracheal, bronchial, and bronchiolar smooth muscle, respectively.1

1 Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).

Synonyms
  • 16,16-dimethyl PGE1
Formal Name 9-​oxo-​11α,​15R-​dihydroxy-​16,​16-​dimethyl-​prost-​13E-​en-​1-​oic acid
CAS Number 41692-15-3
Molecular Formula C22H38O5
Formula Weight 382.5
Formulation A solution in methyl acetate
Purity >98%
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCCCC(C)​(C)​C(O)​\C=C\[C@H]​1C(O)​CC(=O)​C1CCCCCCC(=O)​O

Background Reading

Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).

16,16-dimethyl Prostaglandin E1 is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $57.00 $0.00
5 mg $257.00 $0.00
10 mg $456.00 $0.00
100 mg $3,420.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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