13755 NF-κB (p50) Monoclonal Antibody (Clone 2J10D7)
NF-κB (p50) Monoclonal Antibody (Clone 2J10D7) Workbook Links
Cayman offers a variety of analysis tools to assist you.
Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.
|
Antigen:
a portion of amino acids 150-200 of human NF-κB (p50)
·
Clone designation:
2J10D7
·
Isotype:
IgG1κ
·
Application(s):
IHC and WB
·
NF-κB is a transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis, and inflammation. NF-κB1 (p50), a 50 kDa functional sub-unit of NF-κB, is a member of the Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing a nuclear localization signal, DNA-binding and dimerization domains. NF-κB (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-κB factor. NF-κB (p50) directs the nuclear translocation of NF-κB and is instrumental in its DNA-binding. A pathological role of NF-κB has been suggested in AIDS, hematogenic cancer cell metastasis, and rheumatoid arthritis.
|
Purchase 13755 NF-κB (p50) Monoclonal Antibody (Clone 2J10D7)
Pricing is for North America only. Other customers should contact a distributor in their region.
This product is also available to buy in bulk quantities.
Please contact our
Sales Department
for a quote or to purchase.
Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services.
To ask for assistance with one of our products please contact our Technical Help staff.
Warning This product is not for human or veterinary use.
|
Pricing updated 2010-03-11.
Prices are subject to change without notice.
|
|
|
|
|
