See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Metastasis Associated 1 Family Member 2 Polyclonal Antibody

Cayman Chemical Item Number 13778

p53 Target Protein in Deacetylase Complex; MTA2; MTA-L1 Protein; PID

Metastasis Associated 1 Family Member 2 Polyclonal Antibody

See more

Description

Antigen: synthetic peptide from a portion of human MTA2 amino acids 650-700 · Host: Rabbit · Application(s): IHC and WB · Metastasis Associated 1 Family Member 2 (MTA2), a homologue of human MTA1 and MTA3, is a member of the highly conserved MTA gene family. It is a component of an ATP-dependent nucleosome remodeling (NuRD) and histone deacetylase complex. MTA2 is a nuclear protein that interacts with HDAC1 and HDAC2 and has a functional role in chromatin remodeling and deacetylase activity. MTA2 specifically interacts with p53 and represses p53-dependent transcriptional activation, thereby regulating p53-mediated cell growth arrest and apoptosis. It also inhibits the transcriptional activity of estrogen receptor-α. Northern blot analysis indicates a ubiquitous expression of MTA2.
Synonyms
  • p53 Target Protein in Deacetylase Complex
  • MTA2
  • MTA-L1 Protein
  • PID
Formulation 100 µg of antigen affinity-G-purified IgG in 200 µl PBS containing 0.2% geltain and 0.05% sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity
Chimpanzee MTA2 +
Human MTA2 +
Rhesus monkey MTA2 +

Background Reading

Yao, Y., and Yang, W. The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity. J Biol Chem 278(43) 42560-42568 (2003).

Luo, J., Su, F., Chen, D., et al. Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature 408 377-381 (2000).
Size Price Quantity Subtotal
1 ea $213.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

HDAC1 (human recombinant)
HDAC1 Inhibitor Screening Assay Kit
HDAC2 (human recombinant)
p53DINP1 Polyclonal Antibody New
Show all 4 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?