Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Prostaglandin E₂ Ethanolamide Exclusive

Cayman Chemical Item Number 14012

PGE₂-EA; Dinoprostone Ethanolamide; Prostamide E₂ (CAS 194935-38-1)

Prostaglandin E2 Ethanolamide (CAS 194935-38-1)

See more	Cannabinoids (296) Prostaglandins (513) Receptor Agonist (48) Neuroscience (654)

Description

Prostaglandin E₂ ethanolamide (PGE₂-EA) is an analog of PGE₂ with improved water solubility and stability. PGE₂-EA acts as an agonist with all four known EP receptor subtypes, but with an affinity that is significantly reduced compared to PGE₂.¹ PGE₂ ethanolamide is produced by HCA-7 cells treated with arachidonoyl ethanolamide (AEA).² The physiologic relevance of PGE₂ ethanolamide is not yet established.

1 Ross, R.A., Craib, S.J., Stevenson, L.A., et al. Pharmacological characterization of the anandamide cyclooxygenase metabolite: Prostaglandin E₂ ethanolamide. J Pharmacol Exp Ther 301(3) 900-907 (2002).

2 Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem 277(47) 44877-44885 (2002).

Synonyms	PGE2-EA Dinoprostone Ethanolamide Prostamide E2
Formal Name	N-(2-hydroxyethyl)-9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-amide
CAS Number	194935-38-1
Molecular Formula	C₂₂H₃₇NO₅
Formula Weight	395.5
Formulation	A crystalline solid
Purity	>98%
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCC(O)/C=C/[C@H]1C(O)CC(=O)C1C/C=C\CCCC(=O)NCCO

Background Reading

Ross, R.A., Craib, S.J., Stevenson, L.A., et al. Pharmacological characterization of the anandamide cyclooxygenase metabolite: Prostaglandin E₂ ethanolamide. J Pharmacol Exp Ther 301(3) 900-907 (2002).

Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-arachidonylgycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. J Biol Chem 277(47) 44877-44885 (2002).

Prostaglandin E2 Ethanolamide is available in the following screening libraries:

Size	Price	Quantity	Subtotal
500 µg	$24.00		$0.00
1 mg	$46.00		$0.00
5 mg	$192.00		$0.00
10 mg	$336.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

Arachidonic Acid

Arachidonoyl Ethanolamide

Leukotriene B₄ Ethanolamide

Prostaglandin D₂ Ethanolamide

Prostaglandin E₁ Ethanolamide

Prostaglandin E₂

Prostaglandin E₂ serinol amide Exclusive

Prostaglandin F_2α Ethanolamide

Show all 8 Hide all but first 3

Downloads

	Download Product Insert 156 Kb PDF
	Download Material Safety Data Sheet (MSDS) 15 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs	Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases	Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule	Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Prostaglandin E2 Ethanolamide Exclusive