See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 Exclusive

Cayman Chemical Item Number 14420

Meteneprost; 9-deoxy-9-methylene-16,16-dimethyl PGE2 (CAS 61263-35-2)

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (CAS 61263-35-2)

See more

Description

Meteneprost is a potent analog of prostaglandin E2 (PGE2) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy.1 This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy.1 Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.1,2

1 Wilks, J.W. Pregnancy interception with a combination of prostaglandins: Studies in monkeys. Science 221 1407-1409 (1983).

2 Bundy, G.L., Kimball, F.A., Robert, A., et al. Synthesis and biological activity of 9-deoxo-9-methylene and related prostaglandins. Adv Prostaglandin Thromboxane Res 6 355-363 (1980).

Synonyms
  • Meteneprost
  • 9-deoxy-9-methylene-16,16-dimethyl PGE2
Formal Name 9-​methylene-​11α,​15R-​dihydroxy-​16,​16-​dimethyl-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 61263-35-2
Molecular Formula C23H38O4
Formula Weight 378.6
Formulation A solution in methyl acetate
Purity >98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
CCCCC(C)​(C)​[C@H]​(O)​/C=C/[C@@H]​1[C@@H]​(C/C=C\CCCC(O)​=O)​C(C[C@H]​1O)​=C

Background Reading

Bundy, G.L., Kimball, F.A., Robert, A., et al. Synthesis and biological activity of 9-deoxo-9-methylene and related prostaglandins. Adv Prostaglandin Thromboxane Res 6 355-363 (1980).

Wilks, J.W. Pregnancy interception with a combination of prostaglandins: Studies in monkeys. Science 221 1407-1409 (1983).

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 is available in the following screening library:

Size Price Quantity Subtotal
500 µg $34.00 $0.00
1 mg $65.00 $0.00
5 mg $272.00 $0.00
10 mg $476.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (potassium salt)
Prostaglandin E2
Prostaglandin F1α

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?