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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

11-deoxy Prostaglandin E2

Cayman Chemical Item Number 14520

11-deoxy PGE2 (CAS 35536-53-9)

11-deoxy Prostaglandin E2 (CAS 35536-53-9)

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Description

11-deoxy PGE2 is a stable, synthetic analog of PGE2. In contrast to PGE2 which has bronchodilation effects, 11-deoxy PGE2 is a powerful bronchoconstrictor and contracts human respiratory tract smooth muscle with potencies ranging from 5 to 30 times higher than PGF.1

1 Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).

Synonyms
  • 11-deoxy PGE2
Formal Name 9-​oxo-​15S-​hydroxy-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 35536-53-9
Molecular Formula C20H32O4
Formula Weight 336.5
Formulation A crystalline solid
Purity >99%
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCC[C@H]​(O)​/C=C/[C@H]​([C@H]​1C/C=C\CCCC(O)​=O)​CCC1=O

Background Reading

Chen, J., and Woodward, D.F. Prostanoid-induced relaxation of precontracted cat ciliary muscle is mediated by EP2 and DP receptors. Invest Ophthamol Vis Sci 33 3195-3201 (1992).

Karim, S.M.M., Adaikan, P.G., and Kottegoda, S.R. Prostaglandins and human respiratory tract smooth muscle: Structure activity relationship. Adv Prostaglandin Thromboxane Res 7 969-980 (1980).

11-deoxy Prostaglandin E2 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $46.00 $0.00
5 mg $207.00 $0.00
10 mg $368.00 $0.00
100 mg $2,760.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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