Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…

Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

16-phenyl tetranor Prostaglandin E₂

Cayman Chemical Item Number 14770

16-phenyl tetranor PGE₂ (CAS 38315-44-5)

16-phenyl tetranor Prostaglandin E2 (CAS 38315-44-5)

See more	Prostaglandins (517)

Description

16-phenyl tetranor PGE₂ is a metabolically stable synthetic analog of PGE₂. 16-phenyl tetranor PGE₂ is five times more potent than PGE₂ in causing hypotension in dogs (0.1 µg/kg dose).¹ It is comparable to PGE₂ in inhibiting histamine-induced bronchoconstriction in conscious guinea pigs.¹

1 Johnson, M.R., Schaaf, T.K., Constantine, J.W., et al. Structure activity studies leading to a tissue-selective hypotensive prostaglandin analog, 13,14-dihydro-16-phenyl-ω-tetranor PGE₂. Prostaglandins 20 515-520 (1980).

Synonyms	16-phenyl tetranor PGE2
Formal Name	9-oxo-11α,15S-dihydroxy-16-phenyl-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid
CAS Number	38315-44-5
Molecular Formula	C₂₂H₂₈O₅
Formula Weight	372.5
Formulation	A solution in methyl acetate
Purity	>99%
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard OC(=O)CCC/C=C\CC1C(=O)CC(O)[C@@H]1\C=C\C(O)Cc1ccccc1

Background Reading

Schaaf, T.K., Johnson, M.R., Eggler, J.F., et al. Hypotensive prostaglandin structure activity relationships: 11-Deoxy-16-aryl-ω-tetranor prostaglandins. Adv Prostaglandin Thromboxane Leukot Res 11 313-318 (1983).

Johnson, M.R., Schaaf, T.K., Constantine, J.W., et al. Structure activity studies leading to a tissue-selective hypotensive prostaglandin analog, 13,14-dihydro-16-phenyl-ω-tetranor PGE₂. Prostaglandins 20 515-520 (1980).

16-phenyl tetranor Prostaglandin E2 is available in the following screening libraries:

Size	Price	Quantity	Subtotal
1 mg	$46.00		$0.00
5 mg	$207.00		$0.00
10 mg	$368.00		$0.00
50 mg	$1,610.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

Prostaglandin E₂

Prostaglandin E₂-d₉

Downloads

	Download Product Insert 149 Kb PDF
	Download Material Safety Data Sheet (MSDS) 21 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs	Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases	Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule	Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

16-phenyl tetranor Prostaglandin E2