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14810 17-phenyl trinor Prostaglandin E2
17-phenyl trinor PGE2
(CAS 38315-43-4)
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17-phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist.1,2 17-phenyl trinor PGE2 causes contraction of the guinea pig ileum at a concentration of 11 µM.1 It is slightly less potent than PGE2 in stimulating gerbil colon and rat uterus.2 With an ED50 value of 350 µg/kg, 17-phenyl trinor PGE2 is 4.4 times more potent than PGE2 as an antifertility agent in hamsters.2
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1
Lawrence, R.A., Jones, R.L., Wilson, N.H. Characterization of receptors involved in the direct and indirect actions of prostaglandins E and I on the guinea-pig ileum. Br J Pharmacol 105 271-278 (1992).
2
Miller, W.L., Weeks, J.R., Lauderdale, J.W., et al. Biological activities of 17-phenyl-18,19,20-trinorprostaglandins. Prostaglandins 9 9-18 (1975).
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Pricing updated 2010-02-09.
Prices are subject to change without notice.
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Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.
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