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Prostaglandin F2α Alcohol methyl ether

Cayman Chemical Item Number 16014

PGF2α-OMe; AGN191129 (CAS 143656-18-2)

Prostaglandin F2α Alcohol methyl ether (CAS 143656-18-2)

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Description

Prostaglandin F2α alcohol methyl ether (PGF2α-OMe) is an analog of PGF2α in which the C-1 carboxyl group has been replaced an O-methyl ether. The compound is reported to retain ocular hypotensive properties,1 but the receptors which mediate this activity have not been clearly documented.2

1 Woodward, D.F., and Chan, M.F. Preparation of PGF-1 alcohols as ocular hypotensives. 38204 1-12 (1993).

2 Woodward, D.F., Krauss, A.H., Chen, J., et al. Replacement of the carboxylic acid group of prostaglandin F2α with a hydroxyl or methoxy substituent provides biologically unique compounds. Br J Pharmacol 130 1933-1943 (2000).

Synonyms
  • PGF2α-OMe
  • AGN191129
Formal Name 1-​methoxy-​9α,​11α,​15S-​trihydroxyprosta-​5Z,​13E-​diene
CAS Number 143656-18-2
Molecular Formula C21H38O4
Formula Weight 354.5
Formulation A solution in methyl acetate
Purity >98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCC(O)​/C=C/[C@H]​1C(O)​CC(O)​C1C/C=C\CCCCOC

Background Reading

Woodward, D.F., and Chan, M.F. Preparation of PGF-1 alcohols as ocular hypotensives. 38204 1-12 (1993).

Woodward, D.F., Krauss, A.H., Chen, J., et al. Replacement of the carboxylic acid group of prostaglandin F2α with a hydroxyl or methoxy substituent provides biologically unique compounds. Br J Pharmacol 130 1933-1943 (2000).

Prostaglandin F2α Alcohol methyl ether is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $46.00 $0.00
5 mg $207.00 $0.00
10 mg $368.00 $0.00
50 mg $1,610.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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