Leukotriene A4 Hydrolase Polyclonal Antibody
Cayman Chemical Item Number 160250
LTA4 Hydrolase
Description
Antigen:
recombinant human LTA4 hydrolase
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Host:
rabbit
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Application(s):
WB; other applications not tested
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Leukotriene A4 hydrolase (LTA4 hydrolase) has been cloned from a variety of species including human, rat, and guinea pig.1,2,3,4 These species exhibit ~90% homology at the amino acid level. Human LTA4 hydrolase has a calculated molecular mass of 69 kDa based on the deduced amino acid sequence.1,2
1
Funk, C.D., Rådmark, O., Fu, J.Y., et al. Molecular cloning and amino acid sequence of leukotriene A4 hydrolase. Proc Natl Acad Sci USA 84 6677-6681 (1987).
2
Minami, M., Ohno, S., Kawasaki, H., et al. Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase. Complete primary structure of an enzyme involved in eicosanoid synthesis. J Biol Chem 262 13873-13876 (1987).
3
Makita, N., Funk, C.D., Imai, E., et al. Molecular cloning and functional expression of rat leukotriene A4 hydrolase using the polymerase chain reaction. FEBS Lett 299 273-277 (1992).
4
Minami, M., Mutoh, H., Ohishi, N., et al. Amino-acid sequence and tissue distribution of guinea-pig leukotriene A4 hydrolase. Gene 161 249-251 (1995).
| Synonyms |
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| Formulation |
200 µg protein-A purified IgG |
| Stability |
1 year |
| Storage |
-20°C |
| Shipping |
Wet ice
in continental US; may vary elsewhere
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| Specificity |
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Background Reading
Funk, C.D., Rådmark, O., Fu, J.Y., et al. Molecular cloning and amino acid sequence of leukotriene A4 hydrolase. Proc Natl Acad Sci USA 84 6677-6681 (1987).
Makita, N., Funk, C.D., Imai, E., et al. Molecular cloning and functional expression of rat leukotriene A4 hydrolase using the polymerase chain reaction. FEBS Lett 299 273-277 (1992).
Minami, M., Mutoh, H., Ohishi, N., et al. Amino-acid sequence and tissue distribution of guinea-pig leukotriene A4 hydrolase. Gene 161 249-251 (1995).
Minami, M., Ohno, S., Kawasaki, H., et al. Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase. Complete primary structure of an enzyme involved in eicosanoid synthesis. J Biol Chem 262 13873-13876 (1987).
Mancini, J.A., and Evans, J.F. Cloning and characterization of the human leukotriene A4 hydrolase gene. Eur J Biochem 231 65-71 (1995).
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Pricing updated 2012-05-26.
Prices are subject to change without notice.
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Warning This product is not for human or veterinary use.
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