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5-trans Prostaglandin F2α (tromethamine salt)

Cayman Chemical Item Number 16220

5,6-trans PGF2α (tromethamine salt)

5-trans Prostaglandin F2α (tromethamine salt)

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Description

5-trans PGF2α tromethamine salt is a derivative of 5-trans PGF2α with increased water solubility. Its solubility in PBS is 25 mg/ml compared to 10 mg/ml for 5-trans PGF2α.
Synonyms
  • 5,6-trans PGF2α (tromethamine salt)
Formal Name 9α,​11α,​15S-​trihydroxy-​prosta-​5E,​13E-​dien-​1-​oic acid,​ tris(hydroxymethyl)aminomethane salt
Molecular Formula C20H33O5 · C4H12NO3
Formula Weight 475.6
Formulation A crystalline solid
Purity >99%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O[C@@H]​1[C@H]​(C/C=C/CCCC([O-]​)​=O)​[C@@H]​(/C=C/[C@@H]​(O)​CCCCC)​[C@H]​(O)​C1.[NH3+]​C(CO)​(CO)​CO

Background Reading

Bundy, G.L., Schneider, W.P., Lincoln, F.H., et al. Isolation of a new naturally occurring prostaglandin, 5-trans-PGA2. Synthesis of 5-trans-PGE2 and 5-trans-PGF2α. J Am Chem Soc 94 2124 (1972).

Andersen, N.H., and Leovey, E.M.K. Identification and quantitative determination of prostaglandins by high pressure liquid chromatography. Prostaglandins 6 361-374 (1974).

Brookes, L.G., and Marshall, R.C. The effects of some prostaglandins on respiration in the rabbit. J Pharm Pharmacol 26, Suppl. 80P-81P (1974).

Schneider, W.P., Bundy, G.L., Lincoln, F.H., et al. Isolation and chemical conversions of prostaglandins from Plexaura homamalla: Preparation of prostaglandin E2, prostaglandin F2α, and their 5,6-trans isomers. J Am Chem Soc 99 1222-1232 (1977).

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5-trans Prostaglandin F2α (tromethamine salt) is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $26.00 $0.00
5 mg $117.00 $0.00
10 mg $208.00 $0.00
50 mg $910.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Prostaglandin F2α

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