Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α. It is much less active than PGF2α in antifertility and bronchoconstrictor activities.1,2,3 PGF2β exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF2α.3
1
Miller, W.L., and Sutton, M.J. Relative biological activity of certain prostaglandins and their enantiomers. Prostaglandins1177-84(1976).
2
Gardiner, P.J., and Collier, H.O.J. Specific receptors for prostaglandins in airways. Prostaglandins19819-841(1980).
3
Rosenthale, M.E., Dervinis, A., Kassarich, J., et al. Bronchodilating properties of the prostaglandin F2β in the guinea pig and cat. Prostaglandins3767-772(1973).
Rosenthale, M.E., Dervinis, A., Kassarich, J., et al. Bronchodilating properties of the prostaglandin F2β in the guinea pig and cat. Prostaglandins3767-772(1973).
Gardiner, P.J., and Collier, H.O.J. Specific receptors for prostaglandins in airways. Prostaglandins19819-841(1980).
Miller, W.L., and Sutton, M.J. Relative biological activity of certain prostaglandins and their enantiomers. Prostaglandins1177-84(1976).
Prostaglandin F2β is available in the following screening
libraries: