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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

15-keto Prostaglandin F2α

Cayman Chemical Item Number 16720

15-keto PGF2α (CAS 35850-13-6)

15-keto Prostaglandin F2α (CAS 35850-13-6)

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Description

15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α. in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone.1,2 15-keto PGF2α stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively.1,2 15-keto PGF2α is 10-fold less active than PGF2α in decreasing rabbit intraocular pressure.3

1 Sorensen, P.W., Hara, T.J., Goetz, F.W., et al. F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. Biol Reprod 39 1039-1050 (1988).

2 Moore, A., and Waring, C.P. Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar) PARR. J Exp Biol 199 2307-2316 (1996).

3 Woodward, D.F., Williams, L.S., and Chen, J. Marked differential effects of prostanoid metabolites on rabbit intraocular pressure. Ophthalmic Res 21 428-435 (1989).

Synonyms
  • 15-keto PGF2α
Formal Name 9α,​11α-​dihydroxy-​15-​oxo-​prosta-​5Z,​13E-​dien-​1-​oic acid
CAS Number 35850-13-6
Molecular Formula C20H32O5
Formula Weight 352.5
Formulation A solution in methyl acetate
Purity >98%
λmax 234 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCC(=O)​\C=C/[C@H]​1C(O)​CC(O)​C1C/C=C\CCCC(=O)​O

Background Reading

Woodward, D.F., Williams, L.S., and Chen, J. Marked differential effects of prostanoid metabolites on rabbit intraocular pressure. Ophthalmic Res 21 428-435 (1989).

Moore, A., and Waring, C.P. Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar) PARR. J Exp Biol 199 2307-2316 (1996).

Sorensen, P.W., Hara, T.J., Goetz, F.W., et al. F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. Biol Reprod 39 1039-1050 (1988).

15-keto Prostaglandin F2α is available in the following screening libraries:

Size Price Quantity Subtotal
1 mg $48.00 $0.00
5 mg $216.00 $0.00
10 mg $384.00 $0.00
50 mg $1,680.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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