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9-keto Fluprostenol

Cayman Chemical Item Number 16781

Fluprostenol Prostaglandin E₂ (CAS 156406-33-6)

9-keto Fluprostenol (CAS 156406-33-6)

See more	Prostaglandins (517)

Description

9-keto Fluprostenol is an analog of prostaglandin E₂ (PGE₂) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF_2α and acts primarily through the FP receptor.¹ Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE₂ agonist. However, no studies on the pharmacology of this compound have been published to date.

1 Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F_2α. Nature 250 330-331 (1974).

Synonyms	Fluprostenol Prostaglandin E2
Formal Name	(±)-9-oxo-11α,15R-dihydroxy-16-(3-(trifluoromethyl)phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid
CAS Number	156406-33-6
Molecular Formula	C₂₃H₂₇F₃O₆
Formula Weight	456.5
Formulation	A solution in methyl acetate
Purity	≥95%
λ_max	222, 277 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard OC(=O)CCC/C=C\CC1C(=O)CC(O)[C@@H]1\C=C\C(O)COc1cccc(c1)C(F)(F)F

Background Reading

Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F_2α. Nature 250 330-331 (1974).

Size	Price	Quantity	Subtotal
1 mg	$53.00		$0.00
5 mg	$239.00		$0.00
10 mg	$424.00		$0.00
50 mg	$1,855.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

11-keto Fluprostenol

15-keto Fluprostenol

9-keto Fluprostenol isopropyl ester

Latanoprost-d₄

Prostaglandin E₂

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