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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

8-iso Prostaglandin F3α Exclusive

Cayman Chemical Item Number 16992

8-iso PGF3α; 8-epi PGF3α (CAS 7045-31-0)

8-iso Prostaglandin F3α (CAS 7045-31-0)

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Description

8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of human platelet shape change, where 8-iso PGF2α has an ED50 value of 1 µM.1

1 Praticò, D., Smith, E.M., Violi, F., et al. Local amplification of platelet function by 8-epi prostaglandin F2α is not mediated by thromboxane receptor isoforms. J Biol Chem 271 14916-14924 (1996).

Synonyms
  • 8-iso PGF3α
  • 8-epi PGF3α
Formal Name 9α,​11α,​15S-​trihydroxy-​(8β)-​prosta-​5Z,​13E,​17Z-​trien-​1-​oic acid
CAS Number 7045-31-0
Molecular Formula C20H32O5
Formula Weight 352.5
Formulation A solution in methyl acetate
Purity >98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O[C@@H]​1[C@@H]​(C/C=C\CCCC(O)​=O)​[C@@H]​(/C=C/[C@@H]​(O)​C/C=C\CC)​[C@H]​(O)​C1

8-iso Prostaglandin F3α is available in the following screening library:

Size Price Quantity Subtotal
50 µg $142.00 $0.00
100 µg $270.00 $0.00
500 µg $731.00 $0.00
1 mg $1,988.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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