18212  13,14-dehydro-15-cyclohexyl Carbaprostacyclin

(CAS 145375-81-1)

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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.1,2
1  Kanger, T., Lopp, M., Müraus, A., et al. Synthesis of a novel, optically active 15-nonstereogenic carbaprostacyclin. Synthesis (1992).
2  Kobzar, G., Shelkovnikov, S., Mardla, V., et al. A 15-nonstereogenic carbocyclic analogue of prostacyclin: Effects on human platelets and uterine artery. J Lipid Mediat Cell Signal 10 2443-2449 (1994).


Purchase 18212 13,14-dehydro-15-cyclohexyl Carbaprostacyclin

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Warning This product is not for human or veterinary use.

Pricing updated 2010-03-18.
Prices are subject to change without notice.

Stability of this item is suitable for room temperature overnight shipping. If shipment on ice is desired, it must be requested when the order is placed.

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