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Prostaglandin I3 (sodium salt) Exclusive

Cayman Chemical Item Number 18300

PGI3 (Na salt) (CAS 68324-96-9)

Prostaglandin I3 (sodium salt) (CAS 68324-96-9)

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Description

PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to Δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.1,2

1 Johnson, R.A., Lincoln, F.H., Nidy, E.G., et al. Synthesis and characterization of prostacyclin, 6-ketoprostaglandin F1α, prostaglandin I1, and prostaglandin I3. J Am Chem Soc 100 7690-7704 (1978).

2 Mann, N.J., Warrick, G.E., O'Dea, K., et al. The effect of linoleic, arachidonic, and eicosapentaenoic acid supplementation of prostacyclin production in rats. Lipids 29 157-162 (1994).

Synonyms
  • PGI3 (Na salt)
Formal Name 6,​9α-​epoxy-​11α,​15S-​dihydroxy-​prosta-​5Z,​13E,​17Z-​trien-​1-​oic acid,​ monosodium salt
CAS Number 68324-96-9
Molecular Formula C20H29O5·Na
Formula Weight 372.4
Formulation A lyophilized powder
Purity >99%
Stability 6 months
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O[C@H]​1[C@H]​(/C=C/[C@@H]​(O)​C/C=C\CC)​[C@@H]​(C/C(O2)​=C/CCCC([O-]​)​=O)​[C@@H]​2C1.[Na+]​

Background Reading

Johnson, R.A., Lincoln, F.H., Nidy, E.G., et al. Synthesis and characterization of prostacyclin, 6-ketoprostaglandin F1α, prostaglandin I1, and prostaglandin I3. J Am Chem Soc 100 7690-7704 (1978).

Mann, N.J., Warrick, G.E., O'Dea, K., et al. The effect of linoleic, arachidonic, and eicosapentaenoic acid supplementation of prostacyclin production in rats. Lipids 29 157-162 (1994).

Prostaglandin I3 (sodium salt) is available in the following screening library:

Size Price Quantity Subtotal
50 µg $54.00 $0.00
100 µg $103.00 $0.00
500 µg $432.00 $0.00
1 mg $756.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

Prostaglandin I2 (sodium salt)

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