See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

15-deoxy-Δ12,14-Prostaglandin J2

Cayman Chemical Item Number 18570.1

15-deoxy-Δ12,14-PGJ2 (CAS 87893-55-8)

15-deoxy-Δ12,14-Prostaglandin J2 (CAS 87893-55-8)

See more

Description

This formulation of 15-deoxy-Δ12,14-PGJ2 contains 90-95% of the trans,trans-Δ12,14 isomer, and 5-10% of other double bond isomers which have similar PPARγ ligand activity (see Catalog No. 18570).
Synonyms
  • 15-deoxy-Δ12,14-PGJ2
Formal Name 11-​oxo-​prosta-​5Z,​9,​12E,​14E-​tetraen-​1-​oic acid
CAS Number 87893-55-8
Molecular Formula C20H28O3
Formula Weight 316.4
Formulation A solution in methyl acetate
Purity >98% (isomer mixture)
λmax 306 nm
ε 12
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
O=C1/C([C@@H]​(C/C=C\CCCC(O)​=O)​C=C1)​=C/C=C/CCCC

Background Reading

Kikawa, Y., Narumiya, S., Fukushima, M., et al. 9-Deoxy-Δ912-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma. Proc Natl Acad Sci USA 81 1317-1321 (1984).

Forman, B.M., Tontonoz, P., Chen, J., et al. 15-Deoxy-Δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell 83 803-812 (1995).

Kliewer, S.A., Lenhard, J.M., Willson, T.M., et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83 813-819 (1995).

Fitzpatrick, F.A., and Wynalda, M.A. Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro. J Biol Chem 258 11713-11718 (1983).

Show all 4 Hide all but first 3

15-deoxy-Δ12,14-Prostaglandin J2 is available in the following screening library:

Size Price Quantity Subtotal
1 mg $46.00 $0.00
5 mg $207.00 $0.00
10 mg $368.00 $0.00
50 mg $1,610.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

15-deoxy-Δ12,14-Prostaglandin J2
15-deoxy-Δ12,14-Prostaglandin J2-biotin
15-deoxy-Δ12,14-Prostaglandin J2-d4
PPARγ Ligand Pack
Prostaglandin D2
Prostaglandin J2
T0070907
Show all 7 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?