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Prostaglandin K1

Cayman Chemical Item Number 18800

PGK1 (CAS 69413-73-6)

Prostaglandin K1 (CAS 69413-73-6)

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Description

PGK1 is the 9,11-diketone formed by the oxidation of PGE1 or PGD1. Whether this compound exists biologically is uncertain; it is known to be resistant to metabolism by 15-hydroxy PGDH in vitro.1 In an intact porcine model of balloon angioplasty restenosis, PGK1 was equivalent in activity and potency to PGE1.2

1 Ohno, H., Morikawa, Y., and Hirata, F. Studies on 15-hydroxyprostaglandin dehydrogenase with various prostaglandin analogues. J Biochem 84 1485-1494 (1978).

2 Karnes, H.A., and Maxey, K.M. . (1998).

Synonyms
  • PGK1
Formal Name 9,​11-​dioxo-​15S-​hydroxy-​prost-​13E-​en-​1-​oic acid
CAS Number 69413-73-6
Molecular Formula C20H32O5
Formula Weight 352.5
Formulation A solution in methyl acetate
Purity >98%
λmax 245 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O=C(C1)​[C@H]​(CCCCCCC(O)​=O)​[C@@H]​(/C=C/[C@@H]​(O)​CCCCC)​C1=O

Background Reading

Ohno, H., Morikawa, Y., and Hirata, F. Studies on 15-hydroxyprostaglandin dehydrogenase with various prostaglandin analogues. J Biochem 84 1485-1494 (1978).

Karnes, H.A., and Maxey, K.M. . (1998).

Prostaglandin K1 is available in the following screening library:

Size Price Quantity Subtotal
100 µg $38.00 $0.00
500 µg $171.00 $0.00
1 mg $304.00 $0.00
5 mg $1,330.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

Prostaglandin K2

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