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Leukotriene A₃ methyl ester

Cayman Chemical Item Number 20009

LTA₃ methyl ester (CAS 83851-38-1)

Leukotriene A3 methyl ester (CAS 83851-38-1)

See more	Leukotrienes (90)

Description

Biosynthesis of LTA₃ occurs from 5,8,11-eicosatrienoic acid via the 5-LO pathway¹ and it is the putative intermediate in the biosynthesis of 3-series leukotrienes. LTA₃ as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

1 Jakschik, B.A., Morrison, A.R., and Sprecher, H. Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway. J Biol Chem 258 12797-12800 (1983).

Synonyms	LTA3 methyl ester
Formal Name	5S-trans-5,6-oxido-7E,9E,11Z-eicosatrienoic acid, methyl ester
CAS Number	83851-38-1
Molecular Formula	C₂₁H₃₄O₃
Formula Weight	334.5
Formulation	A solution in hexane containing 1% triethylamine
Purity	>97%
λ_max	279 nm
ε	49
Stability	1 year
Storage	-80°C
Shipping	Dry ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCC/C=C\C=C\C=C\[C@H]1[C@@H](O1)CCCC(OC)=O

Background Reading

Jakschik, B.A., Morrison, A.R., and Sprecher, H. Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway. J Biol Chem 258 12797-12800 (1983).

Leukotriene A3 methyl ester is available in the following screening library:

Bio-active Lipid II Screening Library (96-Well)

Size	Price	Quantity	Subtotal
25 µg	$76.00		$0.00
50 µg	$144.00		$0.00
100 µg	$274.00		$0.00
500 µg	$1,216.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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Leukotriene A3 methyl ester