Cayman Chemical | 18-carboxy dinor Leukotriene B4 | Description • 18-carboxy dinor LTB4 (CAS 102674-12-4)

20170 18-carboxy dinor Leukotriene B₄

18-carboxy dinor LTB₄ (CAS 102674-12-4)

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18-carboxy dinor Leukotriene B₄ (18-carboxy dinor LTB₄) is a β-oxidation metabolite of LTB₄.¹ In the liver, LTB₄ is rapidly metabolized to 20-carboxy LTB₄, which then undergoes β-oxidation to 18-carboxy dinor LTB₄.²

1 Harper, T.W., Garrity, M.J., Murphy, R.C. Metabolism of leukotriene B₄ in isolated rat hepatocytes. Identification of a novel 18-carboxy-19,20-dinor leukotriene B₄ metabolite. J Biol Chem 261 5414-5418 (1986).

2 Shirley, M.A., Murphy, R.C. Metabolism of leukotriene B₄ in isolated rat hepatocytes. Involvement of 2,4-dienoyl-coenzyme a reductase in leukotriene B₄ metabolism. J Biol Chem 265 16288-16295 (1990).

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Pricing updated 2010-03-18.
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