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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

β-Catenin Blocking Peptide

Cayman Chemical Item Number 300013

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Description

Peptide sequence: human β-catenin amino acids 43-62 (APSLSGKGNPEEEDVDTSQV) · To be used in conjunction with Cayman’s β-catenin polyclonal antibody (Catalog No. 100029) to block protein-antibody complex formation during analysis for β-catenin.
Formulation 200 µg of peptide in 200 µl TBS, pH 7.4, containing 0.1% BSA and 0.02% sodium azide
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere

Background Reading

Su, L., Vogelstein, B., and Kinzler, K.W. Association of the APC tumor suppressor protein with catenins. Science 262 1734-1737 (1993).

Nollet, F., Berx, G., Molemans, F., et al. Genomic organization of the human β-catenin gene (CTNNB1). Genomics 32 413-424 (1996).

Yasui, K., Li, G., Wang, Y., et al. β-Catenin in early development of the lancelet embryo indicates specific determination of embroyonic polarity. Dev Growth Differ 44 467-475 (2002).

Chenn, A., and Walsh, C.A. Increased neuronal production, englarged forebrains and cytoachitectural distortions in β-catenin overexpressing transgenic mice. Cereb Cortex 13 599-606 (2003).

Chung, S.S.W., Lee, W.M., and Cheng, C.Y. Study on the formation of specialized inter-sertoli cell junctions in vitro. J Cell Physiol 181 258-272 (1999).

Jaiswell, A.S., Marlow, B.P., Gupta, N., et al. β-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells. Oncogene 21 8414-8427 (2002).

Aberle, H., Butz, S., Stappert, J., et al. Assembly of the cadherin-catenin complex in vitro with recombinant proteins. J Cell Sci 107 3655-3663 (1994).

Olmeda, D., Castel, S., Vilaró, S., et al. β-catenin regulation during the cell cycle: Implications in G2/M and apoptosis. Mol Biol Cell 14 2844-2860 (2003).

Haq, S., Michael, A., Andreucci, M., et al. Stabilization of β-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth. Proc Natl Acad Sci USA 100(8) 4610-4615 (2003).

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Size Price Quantity Subtotal
1 ea $107.00 $0.00
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This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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