See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

Fatty Acid Amide Hydrolase Blocking Peptide

Cayman Chemical Item Number 301600

Oleamide Hydrolase; FAAH; Anandamide Amidohydrolase

See more

Description

Each vial contains 200 µg of lyophilized peptide derived from the C-terminus of rat fatty acid amide hydrolase (FAAH) amino acids sequence 561-579 (CLRFMREVEQLMTPQKQPS).1 This peptide was used as an antigen for production of Cayman’s FAAH polyclonal antibody (Catalog No. 101600) to block protein-antibody complex formation during analysis for FAAH.

1 Tsou, K., Nogueron, M.I., Muthian, S., et al. Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. Neurosci Lett 254 137-140 (1998).

Synonyms
  • Oleamide Hydrolase
  • FAAH
  • Anandamide Amidohydrolase
Formulation A lyophilized peptide
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere

Background Reading

Cravatt, B.F., Giang, D.K., Mayfield, S.P., et al. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384 83-87 (1996).

Boger, D.L., Henriksen, S.J., and Cravatt, B.F. Oleamide: An endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules. Curr Pharm Des 4 303-314 (1998).

Di Marzo, V., Bisogno, T., Melck, D., et al. Interactions between synthetic vanilloids and the endogenous cannabinoid system. FEBS Lett 436 449-454 (1998).

Cravatt, B.F., Demarest, K., Patricelli, M.P., et al. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc Natl Acad Sci USA 98(16) 9371-9376 (2001).

Fowler, C.J., Jonsson, K., and Tiger, G. Fatty acid amide hydrolase: Biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. Biochem Pharmacol 62 517-526 (2001).

Goparaju, S.K., Kurahashi, Y., Suzuki, H., et al. Anandamide amidohydrolase of porcine brain: cDNA cloning, functional expression and site-directed mutagenesis. Biochim Biophys Acta 1441 77-84 (1999).

Van Sickle, M.D., Oland, L.D., Ho, W., et al. Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret. Gastroenterology 121 767-774 (2001).

Tsou, K., Nogueron, M.I., Muthian, S., et al. Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. Neurosci Lett 254 137-140 (1998).

Bisogno, T., Katayama, K., Melck, D., et al. Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells. Implications for cell proliferation and differentiation. Eur J Biochem 254 634-642 (1998).

Katayama, K., Ueda, N., Kurahashi, Y., et al. Distribution of anandamide amidohydrolase in rat tissues with special reference to small intestine. Biochim Biophys Acta 1347 212-218 (1997).

Giang, D.K., and Cravatt, B.F. Molecular characterization of human and mouse fatty acid amide hydrolases. Proc Natl Acad Sci USA 94 2238-2242 (1997).

Show all 11 Hide all but first 3
Size Price Quantity Subtotal
1 ea $107.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

9-Octadecenamide
Arachidonoyl Ethanolamide
CB1 Receptor Polyclonal Antibody
CB2 Receptor Polyclonal Antibody
Fatty Acid Amide Hydrolase Polyclonal Antibody
Fatty Acid Amide Hydrolase Western Ready Control
Show all 6 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?