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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Prostaglandin D1-d4

Cayman Chemical Item Number 312000

PGD1-d4

Prostaglandin D1-d4

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Description

Prostaglandin D1-d4 (PGD1-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD1 by GC- or LC-mass spectrometry. PGD1 is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.1

1 Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem 26 790-799 (1983).

Synonyms
  • PGD1-d4
Formal Name 9α,​15S-​dihydroxy-​11-​oxo-​prost-​13E-​en-​1-​oic-​3,​3,​4,​4-​d4 acid
Molecular Formula C20H30D4O5
Formula Weight 358.5
Formulation A solution in methyl acetate
Purity ≥99% deuterated product
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCCC(O)​/C=C/[C@H]​1C(=O)​CC(O)​C1CCCCCCC(=O)​O

Background Reading

Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J Med Chem 26 790-799 (1983).
Size Price Quantity Subtotal
25 µg $64.00 $0.00
50 µg $122.00 $0.00
100 µg $230.00 $0.00
1 mg $1,792.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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