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12(S)-hydroxy-16-Heptadecynoic Acid Exclusive

Cayman Chemical Item Number 31570

(CAS 148019-74-3)

12(S)-hydroxy-16-Heptadecynoic Acid (CAS 148019-74-3)

See more	Inhibitors (493) Oxylipins (226) Cytochrome P450 (88)

Description

12(S)-hydroxy-16-Heptadecynoic acid is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase.¹ It inhibits prostaglandin ω-hydroxylase with a K_i value of 1.8 µM.¹

1 Burger, A., Clark, J.E., Nishimoto, M., et al. Mechanism-based inhibitors of prostaglandin w-hydrolase: (R)- and (S)-12-hydroxy-16-heptadecynoic acid and 2,2-dimethyl-12-hydroxy-16-heptadecynoic acid. J Med Chem 36 1418-1424 (1993).

Formal Name	12S-hydroxy-16-heptadecynoic acid
CAS Number	148019-74-3
Molecular Formula	C₁₇H₃₀O₃
Formula Weight	282.4
Formulation	A crystalline solid
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCC[C@@H](O)CCCCCCCCCCC(=O)O

Background Reading

Burger, A., Clark, J.E., Nishimoto, M., et al. Mechanism-based inhibitors of prostaglandin w-hydrolase: (R)- and (S)-12-hydroxy-16-heptadecynoic acid and 2,2-dimethyl-12-hydroxy-16-heptadecynoic acid. J Med Chem 36 1418-1424 (1993).

12(S)-hydroxy-16-Heptadecynoic Acid is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
1 mg	$58.00		$0.00
5 mg	$261.00		$0.00
10 mg	$464.00		$0.00
50 mg	$2,030.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Related Products

12(R)-HEPE

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