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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

12-epi Leukotriene B4-d4

Cayman Chemical Item Number 320135

12-epi LTB4-d4

12-epi Leukotriene B4-d4

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Description

12-epi Leukotriene B4-d4 (12-epi LTB4-d4) contains four deuterium atoms at the 6, 7, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 12-epi LTB4 by GC- or LC-mass spectrometry. 12-epi LTB4 is the “unnatural” 12(S) epimer of LTB4. 12-epi LTB4 does not appear in any measurable amount in the LTB4 isomers produced by non-enzymatic hydrolysis of LTA4.1 There are no published reports on the biological activity of 12-epi LTB4.

1 Sala, A., Bolla, M., Zarini, S., et al. Release of leukotriene A4 versus leukotriene B4 from human polymorphonuclear leukocytes. J Biol Chem 271 17944-17948 (1996).

Synonyms
  • 12-epi LTB4-d4
Molecular Formula C20H28D4O4
Formula Weight 340.5
Formulation A solution in acetonitrile
Purity ≥99% deuterated forms (d1-d4)
λmax 270 nm
ε 50
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\CC(O)​\C=C\C=C/C=C/[C@@H]​(O)​CCCC(=O)​O

Background Reading

Sala, A., Bolla, M., Zarini, S., et al. Release of leukotriene A4 versus leukotriene B4 from human polymorphonuclear leukocytes. J Biol Chem 271 17944-17948 (1996).

Size Price Quantity Subtotal
25 µg $256.00 $0.00
50 µg $486.00 $0.00
100 µg $922.00 $0.00
500 µg $4,096.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

12-epi Leukotriene B4
Leukotriene B4
Leukotriene B4-d4

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FAQs

It appears that there is a heterogenous mixture of deuterated species in your deuterated standards; is this normal?

Yes, this is typical of our deuterated products. Our deuterated products contain less than 1 % d0. However, the labeled compounds are not 100% of the deuterated form listed on our product insert. For example, upon analysis of 2-arachidonoyl glycerol-d8 it is expected to see masses associated with the d7, d6, d5 etc.

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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

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