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5(S)-HEPE

Cayman Chemical Item Number 32210

(CAS 92008-51-0)

5(S)-HEPE (CAS 92008-51-0)

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Description

5(S)-HEPE is produced by 5-lipoxygenase catalyzed oxidation of eicosapentaenoic acid (EPA). While the synthesis of 5(S)-HEPE from EPA by tissue homogenates has been demonstrated,1,2 the biological activity of 5(S)-HEPE is poorly documented. It remains to be determined whether this activity differs substantially from that of 5(S)-HETE (Catalog No. 34230).

1 Kulkarni, P.S., Kaufman, P.L., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. J Ocul Pharmacol 3 349-356 (1987).

2 Kulkarni, P.S., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in human and rabbit anterior uvea. Prostaglandins 31 1159-1164 (1986).

Formal Name 5S-​hydroxy-​6E,​8Z,​11Z,​14Z,​17Z-​eicosapentaenoic acid
CAS Number 92008-51-0
Molecular Formula C20H30O3
Formula Weight 318.5
Formulation A solution in ethanol
Purity ≥98%
λmax 236 nm
ε 23
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\C=C/[C@@H]​(O)​CCCC(=O)​O

Background Reading

Kulkarni, P.S., Kaufman, P.L., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. J Ocul Pharmacol 3 349-356 (1987).

Kulkarni, P.S., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in human and rabbit anterior uvea. Prostaglandins 31 1159-1164 (1986).

5(S)-HEPE is available in the following screening library:

Size Price Quantity Subtotal
25 µg $101.00 $0.00
50 µg $192.00 $0.00
100 µg $364.00 $0.00
250 µg $808.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

(±)5-HEPE
5(S)-HETE
Eicosapentaenoic Acid
HEPES Stock Solution (1 M)
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