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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

15(S)-HEPE

Cayman Chemical Item Number 32710

(CAS 86282-92-0)

15(S)-HEPE (CAS 86282-92-0)

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Description

15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. The biosynthesis of 15-HEPE from EPA in guinea pig epidermal enzyme preparations has been documented.1 15(S)-HEPE generated by soybean lipoxygenation of EPA inhibits RBL-1 cell 5-LO with an IC50 value of 28 µM.1

1 Miller, C.C., Yamaguchi, R.Y., and Ziboh, V.A. Guinea pig epidermis generates putative anti-inflammatory metabolites from fish oil polyunsaturated fatty acids. Lipids 24 998-1003 (1989).

Formal Name 15S-​hydroxy-​5Z,​8Z,​11Z,​13E,​17Z-​eicosapentaenoic acid
CAS Number 86282-92-0
Molecular Formula C20H30O3
Formula Weight 318.5
Formulation A solution in ethanol
Purity ≥98%
λmax 236 nm
ε 23
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
CC/C=C\C[C@H]​(O)​/C=C/C=C\C/C=C\C/C=C\CCCC(O)​=O

Background Reading

Miller, C.C., Yamaguchi, R.Y., and Ziboh, V.A. Guinea pig epidermis generates putative anti-inflammatory metabolites from fish oil polyunsaturated fatty acids. Lipids 24 998-1003 (1989).

15(S)-HEPE is available in the following screening library:

Size Price Quantity Subtotal
25 µg $101.00 $0.00
50 µg $192.00 $0.00
100 µg $364.00 $0.00
250 µg $808.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-11. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

(±)15-HEPE
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15-Lipoxygenase (soybean P1) - Purified
Eicosapentaenoic Acid
HEPES Stock Solution (1 M)
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