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8(R)-HETE

Cayman Chemical Item Number 34350

(CAS 105500-09-2)

8(R)-HETE (CAS 105500-09-2)

See more	Lipoxygenase (84) Oxylipins (227)

Description

8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish.^1,2

1 Meijer, L., Brash, A.R., Bryant, R.W., et al. Stereospecific induction of starfish oocyte maturation by (8R)-hydroxyeicosatetraenoic acid. J Biol Chem 261 17040-17047 (1986).

2 Brash, A.R., Baertschi, S.W., Ingram, C.D., et al. On non-cyclooxygenase prostaglandin synthesis in the sea whip coral, Plexaura Homomalla: An 8(R)-lipoxygenase pathway leads to formation of an α-ketol and a racemic prostanoid. J Biol Chem 262 15829-15839 (1987).

Formal Name	8R-hydroxy-5Z,9E,11Z,14Z-eicosatetraenoic acid
CAS Number	105500-09-2
Molecular Formula	C₂₀H₃₂O₃
Formula Weight	320.5
Formulation	A solution in ethanol
Purity	≥98%
λ_max	237 nm
ε	27
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCC/C=C\C/C=C\C=C\C(O)C/C=C\CCCC(=O)O

Background Reading

Meijer, L., Brash, A.R., Bryant, R.W., et al. Stereospecific induction of starfish oocyte maturation by (8R)-hydroxyeicosatetraenoic acid. J Biol Chem 261 17040-17047 (1986).

Piomelli, D., Wang, J.K.T., Sihra, T.S., et al. Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites. Proc Natl Acad Sci USA 86 8550-8554 (1989).

Brash, A.R., Baertschi, S.W., Ingram, C.D., et al. On non-cyclooxygenase prostaglandin synthesis in the sea whip coral, Plexaura Homomalla: An 8(R)-lipoxygenase pathway leads to formation of an α-ketol and a racemic prostanoid. J Biol Chem 262 15829-15839 (1987).

Size	Price	Quantity	Subtotal
25 µg	$126.00		$0.00
50 µg	$239.00		$0.00
100 µg	$454.00		$0.00
250 µg	$1,008.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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