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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

8(R)-HETE

Cayman Chemical Item Number 34350

(CAS 105500-09-2)

8(R)-HETE (CAS 105500-09-2)

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Description

8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish.1,2

1 Meijer, L., Brash, A.R., Bryant, R.W., et al. Stereospecific induction of starfish oocyte maturation by (8R)-hydroxyeicosatetraenoic acid. J Biol Chem 261 17040-17047 (1986).

2 Brash, A.R., Baertschi, S.W., Ingram, C.D., et al. On non-cyclooxygenase prostaglandin synthesis in the sea whip coral, Plexaura Homomalla: An 8(R)-lipoxygenase pathway leads to formation of an α-ketol and a racemic prostanoid. J Biol Chem 262 15829-15839 (1987).

Formal Name 8R-​hydroxy-​5Z,​9E,​11Z,​14Z-​eicosatetraenoic acid
CAS Number 105500-09-2
Molecular Formula C20H32O3
Formula Weight 320.5
Formulation A solution in ethanol
Purity ≥98%
λmax 237 nm
ε 27
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\C=C\C(O)​C/C=C\CCCC(=O)​O

Background Reading

Meijer, L., Brash, A.R., Bryant, R.W., et al. Stereospecific induction of starfish oocyte maturation by (8R)-hydroxyeicosatetraenoic acid. J Biol Chem 261 17040-17047 (1986).

Piomelli, D., Wang, J.K.T., Sihra, T.S., et al. Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites. Proc Natl Acad Sci USA 86 8550-8554 (1989).

Brash, A.R., Baertschi, S.W., Ingram, C.D., et al. On non-cyclooxygenase prostaglandin synthesis in the sea whip coral, Plexaura Homomalla: An 8(R)-lipoxygenase pathway leads to formation of an α-ketol and a racemic prostanoid. J Biol Chem 262 15829-15839 (1987).
Size Price Quantity Subtotal
25 µg $126.00 $0.00
50 µg $239.00 $0.00
100 µg $454.00 $0.00
250 µg $1,008.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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