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tetranor-12(R)-HETE

Cayman Chemical Item Number 34565

8(R)-HHxTrE (CAS 135271-51-1)

tetranor-12(R)-HETE (CAS 135271-51-1)

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Description

Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through β-oxidation from C-1. This metabolite is 8(R)-hydroxy hexadecatrienoic acid (8(R)-HHxTrE) or 2,3,4,5-tetranor 12(R)-HETE.1

1 Nishimura, M., Schwartzman, M.L., Falck, J.R., et al. Metabolism of 12(R)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(R)-HETE) in corneal tissues: Formation of novel metabolites. Arch Biochem Biophys 290 326-335 (1991).

Synonyms
  • 8(R)-HHxTrE
Formal Name 8R-​hydroxy-​4Z,​6E,​10Z-​hexadecatrienoic acid
CAS Number 135271-51-1
Molecular Formula C16H26O3
Formula Weight 266.4
Formulation A solution in ethanol
Purity ≥98%
λmax 234 nm
ε 23
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C[C@@H]​(O)​\C=C\C=C\CCC(=O)​O

Background Reading

Nishimura, M., Schwartzman, M.L., Falck, J.R., et al. Metabolism of 12(R)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(R)-HETE) in corneal tissues: Formation of novel metabolites. Arch Biochem Biophys 290 326-335 (1991).

tetranor-12(R)-HETE is available in the following screening library:

Size Price Quantity Subtotal
25 µg $102.00 $0.00
50 µg $194.00 $0.00
100 µg $367.00 $0.00
250 µg $816.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

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Pricing updated 2012-05-26. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

Related Products

12(R)-HETE
tetranor-12(S)-HETE

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