COX-1 (murine) Blocking Peptide

Cayman Chemical Item Number 360109

Prostaglandin H Synthase 1 (murine); Cyclooxygenase 1 (murine); PGHS-1

Description

Peptide sequence: murine COX-1 amino acids 274-288 (LMRYPPGVPPERQMA) · To be used in conjunction with Cayman’s COX-1 (murine) polyclonal antibody (Catalog No. 160109) to block protein-antibody complex formation during analysis for COX-1.

Synonyms

Prostaglandin H Synthase 1 (murine)
Cyclooxygenase 1 (murine)
PGHS-1

Formulation

A lyophilized peptide

Stability

2 years

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Background Reading

Hla, T., and Maciag, T. Cyclooxygenase gene expression is down-regulated by heparin-binding (acidic fibroblast) growth factor-1 in human endothelial cells. J Biol Chem 266 24059-24063 (1991).

DeWitt, D.L., El-Harith, E.A., Kraemer, S.A., et al. The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases. J Biol Chem 265 5192-5198 (1990).

Smith, W.L., Garavito, R.M., and DeWitt, D.L. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem 271 33157-33160 (1996).

Brannon, T.S., North, A.J., Wells, L.B., et al. Prostacyclin synthesis in ovine pulmonary artery is developmentally regulated by changes in cyclooxygenase-1 gene expression. J Clin Invest 93 2230-2235 (1994).

Samet, J.M., Fasano, M.B., Fonteh, A.N., et al. Selective induction of prostaglandin G/H synthase I by stem cell factor and dexamethasone in mast cells. J Biol Chem 270 8044-8049 (1995).

Funk, C.D., Funk, L.B., Kennedy, M.E., et al. Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. FASEB J 5 2304-2312 (1991).

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Size

Price

Quantity

Subtotal

200 µg

$107.00

$0.00

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