Peptide sequence: human and rat amino acids 130-149 (QHRRKELETRQKQYRWMEWN) · To be used in conjunction with Cayman’s 5-LO polyclonal antiserum (Catalog No. 160402) to block protein-antibody complex formation during analysis for 5-LO.

Shimizu, T., Rådmark, O., and Samuelsson, B. Enzyme with dual lipoxygenase activities catalyzes leukotriene A₄ synthesis from arachidonic acid. Proc Natl Acad Sci USA 81 689-693 (1984).

Pouliot, M., McDonald, P.P., Krump, E., et al. Colocalization of cytosolic phospholipase A₂, 5-lipoxygenase, and 5-lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils. Eur J Biochem 238 250-258 (1996).

Brock, T.G., McNish, R.W., Bailie, M.B., et al. Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence. J Biol Chem 272 8276-8280 (1997).

Chen, X., Naumann, T.A., Kurre, U., et al. cDNA Cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase. J Biol Chem 270 17993-17999 (1995).

Balcarek, J.M., Theisen, T.W., Cook, M.N., et al. Isolation and characterization of a cDNA clone encoding rat 5-lipoxygenase. J Biol Chem 263 13937-13941 (1988).

Dixon, R.A.F., Jones, R.E., Diehl, R.E., et al. Cloning of the cDNA for human 5-lipoxygenase. Proc Natl Acad Sci USA 85 416-420 (1988).

Komatsu, N., Natsui, K., Ueda, N., et al. Immunohistochemical study on arachidonate 5-lipoxygenase in porcine leukocytes and other tissues. J Histochem Cytochem 39 655-662 (1991).

Chopra, A., Ferreira-Alves, D.L., Sirois, P., et al. Cloning of the guinea pig 5-lipoxygenase gene and nucleotide sequence of its promoter. Biochem Biophys Res Commun 185 489-495 (1992).

Matsumoto, T., Funk, C.D., Rådmark, O., et al. Molecular cloning and amino acid sequence of human 5-lipoxygenase. Proc Natl Acad Sci USA 85 26-30 (1988).

Show all 9 Hide all but first 3