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11(R)-HEDE

Cayman Chemical Item Number 37505

11(R)-HEDE

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Description

11(R)-HEDE is produced from 11Z,14Z-eicosadienoic acid by COX in a lipoxygenase-type reaction.1 Spectrophotometric measurement of the conjugated diene absorbance of 11(R)-HEDE is occasionally used to quantify COX activity.2

1 Hemler, M.E., Crawford, C.G., and Lands, W.E.M. Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase. Biochemistry 17 1772-1779 (1978).

2 Koshkin, V., and Dunford, H.B. Reaction of prostaglandin endoperoxide synthase with cis,cis-eicosa-11,14-dienoic acid. J Biol Chem 273 6046-6049 (1998).

Formal Name 11R-​hydroxy-​12E,​14Z-​eicosadienoic acid
Molecular Formula C20H36O3
Formula Weight 324.5
Formulation A solution in ethanol
Purity ≥98%
λmax 234 nm
ε 23
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C=C\[C@H]​(O)​CCCCCCCCCC(O)​=O

Background Reading

Koshkin, V., and Dunford, H.B. Reaction of prostaglandin endoperoxide synthase with cis,cis-eicosa-11,14-dienoic acid. J Biol Chem 273 6046-6049 (1998).

Hemler, M.E., Crawford, C.G., and Lands, W.E.M. Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase. Biochemistry 17 1772-1779 (1978).

11(R)-HEDE is available in the following screening library:

Size Price Quantity Subtotal
25 µg $93.00 $0.00
50 µg $177.00 $0.00
100 µg $335.00 $0.00
250 µg $744.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-05-26. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

(±)11-HEDE
11(S)-HEDE
11(Z),14(Z)-Eicosadienoic Acid

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